Chromatin regulates expression of small RNAs to help maintain transposon methylome homeostasis in Arabidopsis.

ABSTRACT:

Background

Eukaryotic genomes are partitioned into euchromatic and heterochromatic domains to regulate gene expression and other fundamental cellular processes. However, chromatin is dynamic during growth and development and must be properly re-established after its decondensation. Small interfering RNAs (siRNAs) promote heterochromatin formation, but little is known about how chromatin regulates siRNA expression.

Results

We demonstrate that thousands of transposable elements (TEs) produce exceptionally high levels of siRNAs in Arabidopsis thaliana embryos. TEs generate siRNAs throughout embryogenesis according to two distinct patterns depending on whether they are located in euchromatic or heterochromatic regions of the genome. siRNA precursors are transcribed in embryos, a

SUBMITTER: Papareddy RK 

PROVIDER: S-EPMC7499886 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature