Exposure to fine particulate matter and temporal dynamics of episodic memory and depressive symptoms in older women.

ABSTRACT:

Background

Emerging data suggests PM_2.5 (particulate matter with aerodynamic diameter <2.5 μm) may be associated with both earlier declines in episodic memory (EM) and increased depressive symptoms in older adults. Although late-life depressive symptoms are associated with EM, no longitudinal studies have examined the inter-relationship among PM_2.5, depressive symptoms and EM.

Methods

Older women (n = 2,202; aged 67-83 in 1999) enrolled in the Women's Health Initiative Study of Cognitive Aging completed up to eight annual assessments of depressive symptoms (15-item Geriatric Depression Scale) and EM (California Verbal Learning Test). A nationwide spatiotemporal model (1999-2010) was used to estimate ambient PM_2.5 exposure at residential locat

SUBMITTER: Petkus AJ 

PROVIDER: S-EPMC7499893 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature