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Circulating microRNAs and their role in the immune response in triple-negative breast cancer.


ABSTRACT: Breast cancer (BC) is the most common type of cancer in women worldwide, and despite advances in treatments, its incidence and mortality are increasing. Therefore, it is necessary to develop new, non-invasive tests that provide more accurate diagnosis and prognosis in a timely manner. A promising approach is measuring the presence of biomarkers to detect tumors at various stages and determine their specific characteristics, thus allowing for more personalized treatment. MicroRNAs (miRNAs) serve a role in gene expression, primarily by interacting with messenger RNAs, and may be potential biomarkers for detecting cancer. They are detectable in tissues and blood, including plasma and/or serum, are stable and often tumor specific. Also, different miRNAs are associated with specific BC molecula

SUBMITTER: Pina-Sanchez P 

PROVIDER: S-EPMC7499949 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature