Utility of the EULAR Sjogren syndrome disease activity index in Japanese children: a retrospective multicenter cohort study.

ABSTRACT:

Background

The European League Against Rheumatism (EULAR) Sjögren Syndrome Disease Activity Index (ESSDAI) has been utilized to assess Sjögren syndrome-related systemic involvement in adult patients. To date, however, the ESSDAI has not been validated in children with primary Sjögren's syndrome. This study evaluated the applicability of the ESSDAI to Japanese children with primary Sjögren's syndrome.

Methods

The medical records of children who had been diagnosed with Sjogren syndrome at age ≤ 16 years between June 2011 and October 2016 were collected, and their ESSDAIs at initial presentation were calculated. Clinical symptoms and treatment regimens were surveyed by questionnaire, and patients were divided into groups based on ESSDAI and glucocorticoid dosages. The associati

SUBMITTER: Iwata N 

PROVIDER: S-EPMC7499954 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature