Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines.

ABSTRACT: Herbal medicines have accumulated valuable clinical experience in thousands of years of applications in traditional Chinese medicine (TCM) or ethnomedicine. The unique multi-target efficacy on complex diseases made herbal medicines gained a global popularity in recent years. However, the characteristic of multi-component acting on multi-target poses a dilemma for the evaluation of therapeutic efficacy of herbal medicines. Advances in metabolomics enable efficient identification of the various changes in biological systems exposed to different treatments or conditions. The use of serum pharmacochemistry of TCM has significant implications for tackling the major issue in herbal medicines development-pharmacodynamic material basis. Chinmedomics integrates metabolomics and serum pharmacochemis

SUBMITTER: Han Y 

PROVIDER: S-EPMC7500400 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature