Fecal microbiota transplantation in inflammatory bowel disease patients: A systematic review and meta-analysis.

ABSTRACT:

Objectives

Current evidence on fecal microbiota transplantation for inflammatory bowel disease is inconclusive. We conducted a systematic review to gather evidence on the efficacy and safety of fecal microbiota transplantation for inflammatory bowel disease.

Methods

Systematic searches were conducted in PubMed, Scopus, and Web of Science. Clinical remission was considered as the primary endpoint. Pairwise meta-analyses were performed for the randomized controlled studies (Mantel Haenszel, random effects model). Proportion meta-analyses, accounting for weighted pooled rates reported in the interventional studies, were conducted using the mixed effects model. Subgroup analyses considering the type of stool, donor type, and disease subtype were also performed. Cumulative meta-a

SUBMITTER: Caldeira LF 

PROVIDER: S-EPMC7500646 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature