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Serum very long-chain fatty acids (VLCFA) levels as predictive biomarkers of diseases severity and probability of survival in peroxisomal disorders.


ABSTRACT:

Conclusion

VLCFA levels correlate with the severity of the clinical course of ZS, DBP and mild ZSD. The best predictive value for estimating the projected disease severity and survival time is a concentration of C26:0.

SUBMITTER: Stradomska TJ 

PROVIDER: S-EPMC7500652 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Serum very long-chain fatty acids (VLCFA) levels as predictive biomarkers of diseases severity and probability of survival in peroxisomal disorders.

Stradomska Teresa Joanna TJ   Syczewska Małgorzata M   Jamroz Ewa E   Pleskaczyńska Agata A   Kruczek Piotr P   Ciara Elżbieta E   Tylki-Szymanska Anna A  

PloS one 20200918 9


<h4>Conclusion</h4>VLCFA levels correlate with the severity of the clinical course of ZS, DBP and mild ZSD. The best predictive value for estimating the projected disease severity and survival time is a concentration of C26:0. ...[more]

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