Connectome mapping with edge density imaging differentiates pediatric mild traumatic brain injury from typically developing controls: proof of concept.

ABSTRACT:

Background

Although acute neurologic impairment might be transient, other long-term effects can be observed with mild traumatic brain injury. However, when pediatric patients with mild traumatic brain injury present for medical care, conventional imaging with CT and MR imaging often does not reveal abnormalities.

Objective

To determine whether edge density imaging can separate pediatric mild traumatic brain injury from typically developing controls.

Materials and methods

Subjects were recruited as part of the "Therapeutic Resources for Attention Improvement using Neuroimaging in Traumatic Brain Injury" (TRAIN-TBI) study. We included 24 adolescents (χ=14.1 years of age, σ=1.6 years, range 10-16 years), 14 with mild traumatic brain injury (TBI) and 10 typically developi

SUBMITTER: Raji CA 

PROVIDER: S-EPMC7501221 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature