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Dataset Information

Platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios predict tumor size and survival in HCC patients: Retrospective study.


ABSTRACT:

Background

Inflammation is a recognized concomitant of hepatocellular carcinoma (HCC) and its indices are prognostically useful.

Aims

To evaluate two commonly used inflammatory indices, neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), to examine their relationship to maximum tumor diameter (MTD) and to survival.

Methods

A database of 1024 prospectively-accrued HCC patients was examined, who had full baseline tumor parameter data, including CT scan information on HCC size and whose survival was known. Analyses of NLR and PLR were correlated to MDT and to survival. NLR and PLR cutoffs were calculated from receiver operator characteristic curves.

Results

Every MTD pair had significantly different PLR values, for MTD groups of groups

SUBMITTER: Suner A 

PROVIDER: S-EPMC7501491 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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