Subolesin vaccination inhibits blood feeding and reproduction of Haemaphysalis longicornis in rabbits.

ABSTRACT:

Background

Ticks can transmit numerous tick-borne pathogens and cause a huge economic loss to the livestock industry. Tick vaccines can contribute to the prevention of tick-borne diseases by inhibiting tick infestation or reproduction. Subolesin is an antigenic molecule proven to be a potential tick vaccine against different tick species and even some tick-borne pathogens. However, its effectivity has not been verified in Haemaphysalis longicornis, which is a widely distributed tick species, especially in East Asian countries. Therefore, the purpose of this study was to evaluate the effectivity of subolesin vaccination against H. longicornis in a rabbit model.

Methods

Haemaphysalis longicornis (Okayama strain, female, adult, parthenogenetic strain) and Japanese white rabbits

SUBMITTER: Lee SH 

PROVIDER: S-EPMC7501621 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature