A network pharmacology study on analgesic mechanism of Yuanhu-Baizhi herb pair.

ABSTRACT:

Background

Millions of people are suffering from chronic pain conditions, such as headache, arthritis, cancer. Apart from western medicines, traditional Chinese medicines are also well accepted for pain management, especially in Asian countries. Yuanhu-Baizhi herb pair (YB) is a typical herb pair applied to the treatment of stomach pain, hypochondriac pain, headache, and dysmenorrhea, due to its effects on analgesia and sedation. This study is to identify potentially active compounds and the underlying mechanisms of YB in the treatment of pain.

Methods

Compounds in YB were collected from 3 online databases and then screened by bioavailability and drug likeness parameters. Swiss target prediction was applied to obtain targets information of the active compounds. Pain-related

SUBMITTER: Mi B 

PROVIDER: S-EPMC7501664 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature