Clinical performance of decellularized heart valves versus standard tissue conduits: a systematic review and meta-analysis.

ABSTRACT:

Background

Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations. Tissue-engineered (decellularized) heart valves are alternative prostheses that have demonstrated promising early results. The purpose of this systematic review and meta-analysis is to perform robust evaluation of the clinical performance of decellularized heart valves implanted in either outflow tract position, in comparison with standard tissue conduits.

Methods

Systematic searches were conducted in the PubMed, Scopus, and Web of Science databases for articles in which outcomes between decellularized heart valves surgically implanted within either outflow tract

SUBMITTER: Waqanivavalagi SWFR 

PROVIDER: S-EPMC7501674 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature