An empirical examination of sample size effects on population demographic estimates in birds using single nucleotide polymorphism (SNP) data.

ABSTRACT: Sample size is a critical aspect of study design in population genomics research, yet few empirical studies have examined the impacts of small sample sizes. We used datasets from eight diverging bird lineages to make pairwise comparisons at different levels of taxonomic divergence (populations, subspecies, and species). Our data are from loci linked to ultraconserved elements and our analyses used one single nucleotide polymorphism per locus. All individuals were genotyped at all loci, effectively doubling sample size for coalescent analyses. We estimated population demographic parameters (effective population size, migration rate, and time since divergence) in a coalescent framework using Diffusion Approximation for Demographic Inference, an allele frequency spectrum method. Using diverge

SUBMITTER: McLaughlin JF 

PROVIDER: S-EPMC7501783 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature