Modulation of benzofuran structure as a fluorescent probe to optimize linear and nonlinear optical properties and biological activities.

ABSTRACT: The study presents the influence of structure modulation by introducing selected donor and acceptor substituents on optical properties of benzofuran used in biological imaging. As the starting form, 2-(5-formylbenzofuran-2-yl)acetamide described experimentally was used. This molecule contains an aldehyde group as reactive site, through which conjugation with protein occurs. Structure modulation was carried out by attaching additional electron-donating and electron-withdrawing substituents to the amino group, namely -NH₂, -NHCH₃, -NO₂, -OH, and -OCH₃. Studies have shown that the -NH₂, -NHCH₃, -OH, and -OCH₃ substituents do not induce a significant change in the position of maximum absorption and fluorescence relati

SUBMITTER: Krawczyk P 

PROVIDER: S-EPMC7502069 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature