Change in Dynamic Hyperinflation After Bronchoscopic Lung Volume Reduction in Patients with Emphysema.

ABSTRACT:

Background and purpose

In patients with severe emphysema, dynamic hyperinflation is superimposed on top of already existing static hyperinflation. Static hyperinflation reduces significantly after bronchoscopic lung volume reduction (BLVR). In this study, we investigated the effect of BLVR compared to standard of care (SoC) on dynamic hyperinflation.

Methods

Dynamic hyperinflation was induced by a manually paced tachypnea test (MPT) and was defined by change in inspiratory capacity (IC) measured before and after MPT. Static and dynamic hyperinflation measurements were performed both at baseline and 6 months after BLVR with endobronchial valves or coils (treatment group) or SoC (control group).

Results

Eighteen patients underwent BLVR (78% female, 57 (43-67) years, FEV

SUBMITTER: van Dijk M 

PROVIDER: S-EPMC7502448 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature