Dietary Inflammatory Potential and Risk of Crohn's Disease and Ulcerative Colitis.

ABSTRACT:

Background & aims

Inflammation is a potential mechanism through which diet modulates the onset of inflammatory bowel disease. We analyzed data from 3 large prospective cohorts to determine the effects of dietary inflammatory potential on the risk of developing Crohn's disease (CD) and ulcerative colitis (UC).

Methods

We collected data from 166,903 women and 41,931 men in the Nurses' Health Study (1984-2014), Nurses' Health Study II (1991-2015), and Health Professionals Follow-up Study (1986-2012). Empirical dietary inflammatory pattern (EDIP) scores were calculated based on the weighted sums of 18 food groups obtained via food frequency questionnaires. Self-reported CD and UC were confirmed by medical record review. Cox proportional hazards models were used to calculate haza

SUBMITTER: Lo CH 

PROVIDER: S-EPMC7502466 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature