Impact of medications for opioid use disorder among persons hospitalized for drug use-associated skin and soft tissue infections.

ABSTRACT:

Background

Skin and soft tissue infections (SSTI) are common complications of injection drug use. We aimed to determine if rehospitalization and recurrent SSTI differ among persons with opioid use disorder (OUD) hospitalized for SSTI who are initiated on MOUD within 30 days of discharge and those who are not.

Methods

We performed a retrospective analysis of commercially insured adults aged 18 years and older in the U.S. with OUD and hospitalization for injection-related SSTI from 2010-2017. The primary exposure was initiation of MOUD in the 30 days following hospitalization for SSTI. The primary outcomes included 30-day and 1-year 1) all-cause rehospitalization and 2) recurrent SSTI. We calculated the incidence rates for the two groups: MOUD group and no MOUD group for the p

SUBMITTER: Barocas JA 

PROVIDER: S-EPMC7502512 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature