Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension.

ABSTRACT: The six-minute walk test is widely used to assess the severity and prognosis of pulmonary hypertension. However, the pathophysiology underlying a compromised six-minute walk distance is incompletely characterized. The purpose of this study is to evaluate the Fick principle and pulmonary hemodynamic determinants of the six-minute walk distance in patients with suspected pulmonary hypertension. Twenty-nine patients were retrospectively studied and underwent a right heart catheterization for the evaluation of suspected pulmonary hypertension. With the pulmonary artery catheter in place, patients were moved to a treadmill and completed a six-minute walk test. Fick cardiac output and indices of right heart afterload were calculated using continuous measurements of pulmonary vascular pressures,

SUBMITTER: Joseph P 

PROVIDER: S-EPMC7502687 | biostudies-literature | 2020 Jul-Sep

REPOSITORIES: biostudies-literature