CO₂ reduction driven by a pH gradient.

ABSTRACT: All life on Earth is built of organic molecules, so the primordial sources of reduced carbon remain a major open question in studies of the origin of life. A variant of the alkaline-hydrothermal-vent theory for life's emergence suggests that organics could have been produced by the reduction of CO₂ via H₂ oxidation, facilitated by geologically sustained pH gradients. The process would be an abiotic analog-and proposed evolutionary predecessor-of the Wood-Ljungdahl acetyl-CoA pathway of modern archaea and bacteria. The first energetic bottleneck of the pathway involves the endergonic reduction of CO₂ with H₂ to formate (HCOO^-), which has proven elusive in mild abiotic settings. Here we show the reduction of CO₂ with H_2</

SUBMITTER: Hudson R 

PROVIDER: S-EPMC7502746 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature