Assessment of the additional clinical potential of X-ray dark-field imaging for breast cancer in a preclinical setup.

ABSTRACT:

Background

Mammography can identify calcifications up to 50-100 μm in size as a surrogate parameter for breast cancer or ductal carcinoma in situ (DCIS). Microcalcifications measuring <50 µm are also associated with breast cancer or DCIS and are frequently not detected on mammography, although they can be detected with dark-field imaging. This study examined whether additional breast examination using X-ray dark-field imaging can increase the detection rate of calcifications. Advances in knowledge: (1) evaluation of additional modality of breast imaging; (2) specific evaluation of breast calcifications.Implications for patient care: the addition of X-ray dark-field imaging to conventional mammography could detect additional calcifications.

Methods

Talbot-Lau X-ray pha

SUBMITTER: Emons J 

PROVIDER: S-EPMC7502853 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature