Association between red blood cell distribution width and white matter hyperintensities: A large-scale cross-sectional study.

ABSTRACT:

Background

Red blood cell distribution width (RDW) is a strong prognostic marker for various medical conditions, such as ischemic strokes. However, the relationships between higher RDW and the subtypes of white matter hyperintensities (WMHs) remain unclear. Hence, this study aimed to thoroughly evaluate the relationships between RDW and the subtypes of WMHs.

Patients and methods

This cross-sectional study was a retrospective analysis of hospital database (Dongguan Medical System, from April 2015 to February 2017). The presence and subtypes of WMHs were evaluated using Fazekas score with the T2WI-FLAIR brain images from a 1.5-T MRI system. The overall sample was randomly split in half. One of the two split-half samples was used for determining the optimal cutoff value of high

SUBMITTER: Wang M 

PROVIDER: S-EPMC7503097 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature