Short-Term Combined Exercise Improves Inflammatory Profile in the Retina of Obese Mice.

ABSTRACT: Excess of adipose tissue increases the concentration of proinflammatory cytokines, triggering a subclinical inflammatory condition. This inflammatory profile contributes to retina damage, which can lead to retinal dysfunction and reduced vision. Regularly practicing both aerobic and strength exercises is well known for promoting anti-inflammatory effects on different organs in the peripheral and central regions. However, the effects of combined physical exercise (CPE; strength + aerobic) on the inflammatory process in the retina tissue are not yet known. This study aimed to investigate the effects of CPE on the inflammatory profile of the retina in obese mice. Swiss mice were distributed into control, sedentary obese, and trained obese groups. The trained obese group was subjected to short

SUBMITTER: Dantis Pereira de Campos T 

PROVIDER: S-EPMC7503303 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature