Antibody Conjugation of Nanoparticles as Therapeutics for Breast Cancer Treatment.

ABSTRACT: Breast cancer is the most common invasive tumor in women and the second leading cause of cancer-related death. Nanomedicine raises high expectations for millions of patients as it can provide better, more efficient, and affordable healthcare, and it has the potential to develop novel therapeutics for the treatment of solid tumors. In this regard, targeted therapies can be encapsulated into nanocarriers, and these nanovehicles are guided to the tumors through conjugation with antibodies-the so-called antibody-conjugated nanoparticles (ACNPs). ACNPs can preserve the chemical structure of drugs, deliver them in a controlled manner, and reduce toxicity. As certain breast cancer subtypes and indications have limited therapeutic options, this field provides hope for the future treatment of patie

SUBMITTER: Juan A 

PROVIDER: S-EPMC7504566 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature