Spatial analysis of hypospadias cases in northern France: taking clinical data into account.

ABSTRACT:

Background

Strong evidence for a causal role of environmental factors in a congenital anomaly is still difficult to produce. The collection of statistical data is crucial for gaining a better understanding of the epidemiology and pathophysiology of these anomalies. We aimed to evaluate spatial variations in hypospadias within our region and it's association to socioeconomic and ecological factors, taking clinical data into account.

Methods

All boys with hypospadias born in northern France and seen in Lille University Medical Center (Lille, France) between 1999 and 2012 were included in the analysis. We retrospectively collected geographic data, clinical data (especially known confounding factors associated with an elevated risk of hypospadias), and demographic, socio-economi

SUBMITTER: Lauriot Dit Prevost A 

PROVIDER: S-EPMC7504625 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature