Use of a Plasmodium vivax genetic barcode for genomic surveillance and parasite tracking in Sri Lanka.

ABSTRACT:

Background

Sri Lanka was certified as a malaria-free nation in 2016; however, imported malaria cases continue to be reported. Evidence-based information on the genetic structure/diversity of the parasite populations is useful to understand the population history, assess the trends in transmission patterns, as well as to predict threatening phenotypes that may be introduced and spread in parasite populations disrupting elimination programmes. This study used a previously developed Plasmodium vivax single nucleotide polymorphism (SNP) barcode to evaluate the population dynamics of P. vivax parasite isolates from Sri Lanka and to assess the ability of the SNP barcode for tracking the parasites to its origin.

Methods

A total of 51 P. vivax samples collected during 2005-2011, mai

SUBMITTER: Dewasurendra RL 

PROVIDER: S-EPMC7504840 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature