Developmental Trajectories of Cortical Thickness in Relation to Schizotypy During Adolescence.

ABSTRACT: Investigating potential gray matter differences in adolescents presenting higher levels of schizotypy personality traits could bring further insights into the development of schizophrenia spectrum disorders. Research has yet to examine the morphological correlates of schizotypy features during adolescence prospectively, and no information is available on the developmental trajectories from adolescence to adulthood. We employed mixed model regression analysis to investigate developmental trajectories of cortical thickness (CT) in relation to schizotypy dimensions in a cohort of 109 adolescents from the general population for whom MRI-scans were acquired over a 5-year period, culminating in a total of 271 scans. Structural data were processed with FreeSurfer software, statistical analyses we

SUBMITTER: Derome M 

PROVIDER: S-EPMC7505202 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature