Changing epidemiology of nephrotic syndrome in Nigerian children: A cross-sectional study.

ABSTRACT:

Background

Recent reports from small studies in West Africa suggest that Black children may have high rate of steroid sensitivity nephrotic syndrome (SSNS) contrary to long held knowledge. Herein, we determined the proportion of children with idiopathic nephrotic syndrome (INS) who achieved complete remission with steroid therapy and identified factors associated with complete remission.

Methods

We reviewed the medical records of 241 children with INS in two centres in Lagos from 2010 to 2019. We extracted demographic data, clinical features, laboratory values at the time of diagnosis, and receipt and response to steroids and other immunosuppressants.

Results

The median (interquartile range) age at diagnosis of INS was 5.1 (3.0-8.7) years and boys were 60.2% of the st

SUBMITTER: Esezobor CI 

PROVIDER: S-EPMC7505420 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature