Meconium microbiome and its relation to neonatal growth and head circumference catch-up in preterm infants.

ABSTRACT: The purpose was identify an association between meconium microbiome, extra-uterine growth restriction, and head circumference catch-up.

Materials and methods

Prospective study with preterm infants born <33 weeks gestational age (GA), admitted at Neonatal Unit and attending the Follow-Up Preterm Program of a tertiary hospital. Excluded out born infants; presence of congenital malformations or genetic syndromes; congenital infections; HIV-positive mothers; and newborns whose parents or legal guardians did not authorize participation. Approved by the institution's ethics committee. Conducted 16S rRNA sequencing using PGM Ion Torrent meconium samples for microbiota analysis.

Results

Included 63 newborns, GA 30±2.3 weeks, mean weight 1375.80±462.6 grams, 68.3% adequate weight for

SUBMITTER: Terrazzan Nutricionist AC 

PROVIDER: S-EPMC7505439 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature