Autonomic modulation before and after paroxysmal atrial fibrillation events in patients with ischemic heart disease.

ABSTRACT:

Background

The autonomic activity plays a critical role in generating paroxysmal atrial fibrillation (PAF). This study aimed to evaluate the changes in the autonomic nerve activity before and after PAF events in patients with and without ischemic heart disease (IHD).

Methods

The study included 49 patients (71.43 ± 12.24 years old, 26 males) with PAF events lasting more than 30 s during 24-hr ambulatory Holter monitoring. The 20-min intervals before and after PAF events were divided into eight segments of 5 min each. Heart rate variability (HRV) analyses of the time and frequency domains were applied to each time segment.

Results

Patients with IHD had significant increases in the root mean square successive differences (r-MSSD, p = .008) and HF component (p = .04), fol

SUBMITTER: Ernie Liao TW 

PROVIDER: S-EPMC7507060 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature