Sensaas: Shape-based Alignment by Registration of Colored Point-based Surfaces.

ABSTRACT: sensaas is a tool developed for aligning and comparing molecular shapes and sub-shapes. Alignment is obtained by registration of 3D point-based representations of the van der Waals surface. The method uses local properties of the shape to identify the correspondence relationships between two point clouds containing up to several thousand colored (labeled) points. Our rigid-body superimposition method follows a two-stage approach. An initial alignment is obtained by matching pose-invariant local 3D descriptors, called FPFH, of the input point clouds. This stage provides a global superimposition of the molecular surfaces, without any knowledge of their initial pose in 3D space. This alignment is then refined by optimizing the matching of colored points. In our study, each point is colored ac

SUBMITTER: Douguet D 

PROVIDER: S-EPMC7507133 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature