Maternal antibiotic use and vaginal infections in the third trimester of pregnancy and the risk of obesity in preschool children.

ABSTRACT:

Background/objectives

Several exposures during pregnancy are associated with offspring body mass index (BMI). The objective of this study was to evaluate whether third trimester antibiotic use and vaginal infections are associated with BMI in preschool children.

Subjects/methods

The study population included singletons from the NINFEA birth cohort with available anthropometric measurements at the age of 4 (3151 born with vaginal and 1111 born with caesarean delivery). Self-reported use of antibiotics and the presence of vaginal infection in the third trimester were analysed in association with the child's BMI, classified into three categories: thinness, normal and overweight/obesity, using both the International Obesity Task Force (IOTF) and the World Health Organization (WH

SUBMITTER: Isaevska E 

PROVIDER: S-EPMC7507215 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature