Persistent HIV-controllers are more prone to spontaneously clear HCV: a retrospective cohort study.

ABSTRACT:

Introduction

HIV-controllers have the ability to spontaneously maintain viraemia at low or undetectable levels in the absence of antiretroviral treatment. Furthermore, HIV-controllers seem to have a superior capacity to spontaneously clear hepatitis C virus (HCV) compared to non HIV-controllers. Some of these subjects eventually lose HIV-controller status (transient controllers), whereas some HIV-controllers show a persistent natural HIV control (persistent controllers). We aimed to analyse whether persistent controllers have superior capacity to spontaneously clear HCV compared to transient controllers.

Methods

We recruited HIV-controllers from January 1981 up to October 2016 with available antibodies to HCV (anti-HCV) data (n = 744). Factors associated with HIV spontaneous

SUBMITTER: Dominguez-Molina B 

PROVIDER: S-EPMC7507465 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature