Postoperative cognitive change after cardiac surgery predicts long-term cognitive outcome.

ABSTRACT:

Objectives

Postoperative cognitive dysfunction (POCD) is a common consequence of coronary artery bypass grafting. However, domain-specific associations between postoperative changes and long-term performance are poorly known. The aim of this study was to investigate whether domain-specific cognitive changes after cardiac surgery predict long-term cognitive outcome.

Materials and methods

We assessed 100 patients (86 men, mean age 60) before coronary artery bypass grafting, with re-examinations after one week, three months, and a mean of 6.7 years. The extensive neuropsychological test battery was organized into seven functional cognitive domains. Cognitive decline and improvement were defined with the reliable change index derived from 17 matching healthy controls. Analyses w

SUBMITTER: Relander K 

PROVIDER: S-EPMC7507551 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature