Plants expressing murine pro-apoptotic protein Bid do not have enhanced PCD.

ABSTRACT:

Objectives

The purpose of this study was to explore whether plant programmed cell death (PCD) cascade can sense the presence of the animal-only BH3 protein Bid, a BCL-2 family protein known to play a regulatory role in the signaling cascade of animal apoptosis.

Results

We have expressed the mouse pro-apoptotic protein Bid in Arabidopsis thaliana and in Nicotiana tabacum. We did not obtain any transformed plant constitutively expressing the truncated protein (tBid-i.e. the caspase-activated form) whereas ectopic expression of the full-length protein (flBid) does not interfere with growth and development of the transformed plants. To verify whether the presence of this animal pro-apoptotic protein modified stress responses and PCD execution, both N. tabacum and A. thaliana pla

SUBMITTER: Manara A 

PROVIDER: S-EPMC7507633 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature