Identification of single nucleotide variants in the Moroccan population by whole-genome sequencing.

ABSTRACT:

Background

Large-scale human sequencing projects have described around a hundred-million single nucleotide variants (SNVs). These studies have predominately involved individuals with European ancestry despite the fact that genetic diversity is expected to be highest in Africa where Homo sapiens evolved and has maintained a large population for the longest time. The African Genome Variation Project examined several African populations but these were all located south of the Sahara. Morocco is on the northwest coast of Africa and mostly lies north of the Sahara, which makes it very attractive for studying genetic diversity. The ancestry of present-day Moroccans is unknown and may be substantially different from Africans found South of the Sahara desert, Recent genomic data of Taforal

SUBMITTER: Crooks L 

PROVIDER: S-EPMC7507649 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature