Hydrogen-bonded host-guest systems are stable in ionic liquids.

ABSTRACT: We show that H-bonded host-guest systems associate in ionic liquids (ILs), pure salts with melting point below room temperature, in which dipole-dipole electrostatic interactions should be negligible in comparison with dipole-charge interactions. Binding constants (K_a) obtained from titrations of four H-bonded host-guest systems in two organic solvents and two ionic liquids yield smaller yet comparable K_a values in ionic liquids than in organic solvents. We also detect the association event using force spectroscopy, which confirms that the binding is not solely due to (de)solvation processes. Our results indicate that classic H-bonded host-guest supramolecular chemistry takes place in ILs. This implies that strong H-bonds are only moderately affected by surroundings c

SUBMITTER: Naranjo T 

PROVIDER: S-EPMC7508985 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature