Cost-effectiveness analysis of alternative colon cancer screening strategies in the context of the French national screening program.

ABSTRACT:

Background

A nationwide colorectal cancer (CRC) screening program was set up in France from 2009 for average-risk, asymptomatic people aged 50-74 years based on an immunochemical fecal occult blood test [faecal immunochemical test (FIT)] every 2 years, followed by colonoscopy if positive. The European standard recommends a participation rate of 45% for the program to be cost-effective, yet the latest published rate in France was 34%. The objective of this study was to compare the cost effectiveness of screening alternatives taking real-world participation rates into account.

Methods

Eight screening strategies were compared, based either on a screening test (Guaiac or FIT testing, blood-based, stool DNA, computed tomography colonography, colon capsules, and sigmoidoscopy) fol

SUBMITTER: Barre S 

PROVIDER: S-EPMC7509710 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature