Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study.

ABSTRACT:

Objectives

Gallstone disease (GSD) can be caused by various health and clinical factors such as obesity, dyslipidaemia and an unhealthy diet, all of which are associated with higher high-sensitivity C reactive protein (hs-CRP) concentrations. Whether hs-CRP represents an independent risk factor for GSD is still unclear. We prospectively investigated hs-CRP in relation to the occurrence of GSD based on the Kailuan study.

Study design

Prospective cohort study.

Setting

The Kailuan cohort study was conducted in Tangshan City in northern China.

Participants

95 319 participants who were free from GSD were recruited in this study. Epidemiological data, anthropometric parameters and biochemical data of participants were collected.

Primary and secondary outcome measu

SUBMITTER: Liu T 

PROVIDER: S-EPMC7509952 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature