Reproductive sequelae of parental severe illness before the pandemic: implications for the COVID-19 pandemic.

ABSTRACT:

Objective

To investigate, with pre-COVID-19 data, whether parental exposure to severe systemic infections near the time of conception is associated with pregnancy outcomes.

Design

Retrospective cohort study.

Setting

Population-based study covering births within the United States from 2009 to 2016.

Participants

The IBM MarketScan Research database covers reimbursed health care claims data on inpatient and outpatient encounters that are privately insured through employment-sponsored health insurance. Our analytic sample included pregnancies to paired fathers and mothers.

Interventions(s)

Parental preconception exposure (0-6 months before conception) to severe systemic infection (e.g., sepsis, hypotension, respiratory failure, critical care evaluation).

SUBMITTER: Kasman AM 

PROVIDER: S-EPMC7510413 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature