Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation : A Comparative Modeling Study.

ABSTRACT:

Background

Surveillance with annual mammography and breast magnetic resonance imaging (MRI) is recommended for female survivors of childhood cancer treated with chest radiation, yet benefits, harms, and costs are uncertain.

Objective

To compare the benefits, harms, and cost-effectiveness of breast cancer screening strategies in childhood cancer survivors.

Design

Collaborative simulation modeling using 2 Cancer Intervention and Surveillance Modeling Network breast cancer models.

Data sources

Childhood Cancer Survivor Study and published data.

Target population

Women aged 20 years with a history of chest radiotherapy.

Time horizon

Lifetime.

Perspective

Payer.

Intervention

Annual MRI with or without mammography, starting at age 25, 30,

SUBMITTER: Yeh JM 

PROVIDER: S-EPMC7510774 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature