A novel risk-scoring system for predicting lymph node metastasis of rectal neuroendocrine tumors.

ABSTRACT:

Aim

Although rectal neuroendocrine tumors (NETs) are considered to be rare low-grade malignancies when lymph node metastasis (LNM) is present, their degree of malignancy is comparable to that of colorectal cancer (CRC). However, it remains unclear as to which patients require radical lymph node dissection. The aim of this study was to elucidate the risk factors for LNM and develop a risk-scoring system for LNM to help determine appropriate therapeutic approaches.

Methods

In this study, we examined 103 patients with rectal NETs who underwent local resection (n = 55) or radical resection with LN dissection (n = 48). We evaluated each pathological feature, including the depth of submucosal invasion (SM depth) and tumor budding grade.

Results

According to our univariate a

SUBMITTER: Chida K 

PROVIDER: S-EPMC7511567 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature