Cardiac structure and function in schizophrenia: cardiac magnetic resonance imaging study.

ABSTRACT:

Background

Heart disease is the leading cause of death in schizophrenia. However, there has been little research directly examining cardiac function in schizophrenia.

Aims

To investigate cardiac structure and function in individuals with schizophrenia using cardiac magnetic resonance imaging (CMR) after excluding medical and metabolic comorbidity.

Method

In total, 80 participants underwent CMR to determine biventricular volumes and function and measures of blood pressure, physical activity and glycated haemoglobin levels. Individuals with schizophrenia ('patients') and controls were matched for age, gender, ethnicity and body surface area.

Results

Patients had significantly smaller indexed left ventricular (LV) end-diastolic volume (effect size d = -0.82, P = 0

SUBMITTER: Osimo EF 

PROVIDER: S-EPMC7511899 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature