Ontology highlight
ABSTRACT:
SUBMITTER: Krivanek J
PROVIDER: S-EPMC7511944 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Nature communications 20200923 1
Understanding cell types and mechanisms of dental growth is essential for reconstruction and engineering of teeth. Therefore, we investigated cellular composition of growing and non-growing mouse and human teeth. As a result, we report an unappreciated cellular complexity of the continuously-growing mouse incisor, which suggests a coherent model of cell dynamics enabling unarrested growth. This model relies on spatially-restricted stem, progenitor and differentiated populations in the epithelial ...[more]