Which is better for mothers and babies: fresh or frozen-thawed blastocyst transfer?

ABSTRACT:

Background

In recent years, there have been many reports on the pregnancy outcomes of fresh blastocyst transfer (BT) and frozen-thawed BT, but the conclusions are controversial and incomplete. To compare the pregnancy outcomes, maternal complications and neonatal outcomes of fresh and frozen-thawed BT in the context of in vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) cycles, we conducted a meta-analysis.

Methods

A meta-analysis was conducted by searching the PubMed, Embase, and Cochrane Library databases through May 2020. Data were extracted independently by two authors.

Results

Fifty-four studies, including 12 randomized controlled trials (RCTs), met the inclusion criteria. Fresh BT was associated with a lower implantation rate, pregnancy rate, o

SUBMITTER: Yang M 

PROVIDER: S-EPMC7513314 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature