Strong ion and weak acid analysis in severe preeclampsia: potential clinical significance.

ABSTRACT:

Background

The influence of common disturbances seen in preeclampsia, such as changes in strong ions and weak acids (particularly albumin) on acid-base status, has not been fully elucidated. The aims of this study were to provide a comprehensive acid-base analysis in severe preeclampsia and to identify potential new biological predictors of disease severity.

Methods

Fifty women with severe preeclampsia, 25 healthy non-pregnant- and 46 healthy pregnant controls (26-40 weeks' gestation), were enrolled in this prospective case-control study. Acid-base analysis was performed by applying the physicochemical approach of Stewart and Gilfix.

Results

Mean [sd] base excess was similar in preeclamptic- and healthy pregnant women (-3.3 [2.3], and -2.8 [1.5] mEq/L respectively). I

SUBMITTER: Ortner CM 

PROVIDER: S-EPMC7513390 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature