Stratifying malaria receptivity in Bangladesh using archived rapid diagnostic tests.

ABSTRACT:

Background

Surveillance of low-density infections and of exposure to vectors is crucial to understand where malaria elimination might be feasible, and where the risk of outbreaks is high. Archived rapid diagnostic tests (RDTs), used by national malaria control and elimination programs for clinical diagnosis, present a valuable, yet rarely used resource for in-depth studies on malaria epidemiology.

Methods

1022 RDTs from two sub-Districts in Bangladesh (Alikadam and Kamalganj) were screened by qPCR for low-density Plasmodium falciparum and Plasmodium vivax infections, and by ELISA for Anopheles salivary gland antibodies as a marker for exposure to vectors.

Results

Concordance between RDT and qPCR was moderate. qPCR detected 31/1022 infections compared to 36/1022 diagno

SUBMITTER: Sagna AB 

PROVIDER: S-EPMC7513508 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature