Long-term efficacy of surgical resection with or without adjuvant therapy for treatment of secondary glioblastoma in adults.

ABSTRACT:

Background

There are limited studies on treatment strategies and associated clinical outcomes in patients with secondary glioblastoma (sGBM). We sought to investigate the prognostic factors and treatment decisions in a retrospective cohort of patients with sGBM.

Methods

One hundred and seventy-one patients with sGBM who met the screening criteria were included in this study. Kaplan-Meier survival analysis and Cox survival analysis were used to detect prognostic factors. R (v3.5.0) and SPSS software (v25.0, IBM) were used to perform statistical analyses.

Results

The median overall survival was 303 days (range 23-2237 days) and the median progression-free survival was 229 days (range 33-1964 days) in patients with sGBM. When assessing the relationship between adjuvant t

SUBMITTER: Huang R 

PROVIDER: S-EPMC7513886 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature