GFAP expression in the optic nerve and increased H₂S generation in the integration centers of the rainbow trout (Oncorhynchus mykiss) brain after unilateral eye injury.

ABSTRACT: Hydrogen sulfide (H₂S) is considered as a protective factor against cardiovascular disorders. However, there are few reports on the effects of H₂S in the central nervous system during stress or injury. Previous studies on goldfish have shown that astrocytic response occurs in the damaged and contralateral optic nerves. Glial fibrillary acidic protein (GFAP) concentration in the optic nerves of rainbow trout has not been measured previously. This study further characterized the astrocytic response in the optic nerve and the brain of a rainbow trout (Oncorhynchus mykiss) after unilateral eye injury and estimated the amount of H₂S-producing enzyme cystathionine β-synthase (CBS) in the brain of the rainbow trout. Within 1 week after unilateral eye injury, a pro

SUBMITTER: Pushchina EV 

PROVIDER: S-EPMC7513979 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature