The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.

ABSTRACT: Socioeconomic status (SES), living in poverty, and other social determinants of health contribute to health disparities in the United States. African American (AA) men living below poverty in Baltimore City have a higher incidence of mortality when compared to either white males or AA females living below poverty. Previous studies in our laboratory and elsewhere suggest that environmental conditions are associated with differential gene expression (DGE) patterns in peripheral blood mononuclear cells (PBMCs). DGE have also been associated with hypertension and cardiovascular disease (CVD) and correlate with race and sex. However, no studies have investigated how poverty status associates with DGE between male and female AAs and whites living in Baltimore City. We examined DGE in 52 AA and w

SUBMITTER: Arnold NS 

PROVIDER: S-EPMC7514036 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature