Associations between genetic polymorphisms in interleukin-10 and hematological oncology: evidence from a meta-analysis.

ABSTRACT: Background: Associations between polymorphisms in interleukin-10 (IL-10) and hematological oncology were already explored by many genetic association studies, with controversial findings. The aim of this meta-analysis was to more comprehensively analyze associations between polymorphisms in IL-10 and hematological oncology by combing the results of all relevant studies.Methods: Eligible articles were searched from Pubmed, Embase, WOS and CNKI. The latest literature searching update was performed on 8 October 2019. We used Review Manager to combine the results of eligible studies.Results: Forty-one articles were included in this meta-analysis. IL-10 rs1800890 polymorphism was found to be significantly associated with hematological oncology under AA

SUBMITTER: Hong P 

PROVIDER: S-EPMC7515506 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature